Nigella sativa Linn has been used for centuries as a medicinal plant and possesses a number of pharmacological properties. In the present study the chloroform and methanol seed extracts of N.sativa were tested for their antibacterial activity against selected microbes at different concentrations of 300 µg, 600 µg and 900 µg respectively. Preliminary phytochemical screening of the seed extracts were also carried out. The results obtained for antibacterial study showed that the extracted fractions exhibited significant antibacterial activity against Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Proteus mirabilis and exhibited no activity against Pseudomonas aeruginosa. Streptomycin was used as the standard reference drug in this study. The outcome of this study signifies the potentiality of N.sativa against bacterial pathogens.
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